|  |   |  |  | Personnel and staff Callisto has a well-respected research and
            management team with many years of experience in the pharmaceutical
            and biotechnology industry. Members of the management
            team have particular
            experience in the development of anti-cancer agents, including the
            platinum anticancer drug ParaplatinTM and genasense. The
            team has specialized in early stage research and development, having
            successfully identified and developed preclinical drug canidates
            and brought them to the clinic. The management team was also responsible
            for preclinical discovery of
            UT231B, a drug
            currently in human testing for hepatitis C by United
            Therapeutics.
 
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